PD-L1 antibody

Catalog No. ABIN7266180

This anti-PD-L1 antibody is a Rabbit Monoclonal antibody detecting PD-L1 in WB, FACS, ELISA and InhA. Suitable for Human.

Quick Overview for PD-L1 antibody (ABIN7266180)

Target: PD-L1 (CD274 (PD-L1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PD-L1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Inhibition Assay (InhA)

Product Details anti-PD-L1 Antibody

Purpose: PD-L1/CD274 Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Purity: ≥95 % purity by SDS-PAGE

Immunogen: Recombinant protein of human PD-L1/CD274.

Isotype: IgG

Application Details

Application Notes: Elisa,1:500 - 1:2000,WB,1:500 - 1:2000,FC,1:50 - 1:200,Inhibition,1 μg/ul

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.09 % sodium azide, 50 % glycerol, pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PD-L1

Target: PD-L1 (CD274 (PD-L1))

Alternative Name: PD-L1

Background: Programmed death-ligand 1 (PD-L1) is a 40 kDa type 1 transmembrane protein that suppresses immune system. PD-L1 is expressed in hematopoietic and non-hematopoietic cells including T cells and B cells and various types of tumor cells. PD-L1 binds to its receptor Programmed death 1 (PD1). During infection or inflammation, PD1-PD-L1 interaction is important for preventing autoimmunity. In tumor microenvironments, PD1-PD-L1 interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human cancers. In recent years, PD-L1 has become an important biomarker and immunotherapy target for many types of malignancies.,B7-H,B7H1,PDL1,PD-L1,PDCD1L1,PDCD1LG1,CD274,Immunology & Inflammation,CD markers,PD-L1

Molecular Weight: 20kDa/33kDa

Gene ID: 29126

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints